SLA 처리된 임플란트 표면에서 상온대기압 공기 플라즈마가 세포활성에미치는 영향
Effects of non-thermal atmospheric pressure air plasma exposure on SLA-treated implant in relation to cellular activity
서혜연, 이은정, 권재성, 임수연, 김광만, 김경남,
소속 상세정보
서혜연 ( Seo Hye-Yeon ) - 연세대학교 치과대학 치과생체재료공학교실 및 연구소
이은정 ( Lee Eun-Jung ) - 연세대학교 치과대학 치과생체재료공학교실
권재성 ( Kwon Jae-Sung ) - 연세대학교 치과대학 치과생체재료공학교실
임수연 ( Im Su-Yeon ) - 연세대학교 치과대학 치과생체재료공학교실
김광만 ( Kim Kwang-Man ) - 연세대학교 치과대학 치과생체재료공학교실
김경남 ( Kim Kyoung-Nam ) - 연세대학교 치과대학 치과생체재료공학교실
KMID : 0362220130400040309
Abstract
Surface properties of titanium implants are known as important factors for successful osseointegration. The purpose of this research is to apply recently highlighted non-thermal atmospheric pressure plasma jet (NTAPPJ) on sand blast, large grit, acid etching(SLA) treated Titaniumi surface to improve the hydrophilicity and cellular response. The change in the chemical binding state of SLA-treated Ti before and after the NTAPPJ treatment were determined using field emission scanning electron icroscope, optical surface roughness system, X-ray photoelectron spectroscope, and water contact angle measuring system. MC3T3-E1 cells (murine osteoblastic cell line) attachments and proliferations were examined by the PrestoBlue reagent. This study found that the compressed air-based NTAPPJ treatment on SLA-treated Ti surface significantly increased the hydrophilicity and MC3T3-E1 cell attachments and proliferations. These results suggested that compressed air-based NTAPPJ treatment on the SLA-treated Ti surface had an effect on increasing attachments and proliferations of MC3T3-E1 cell for better osseointegration in vitro.
키워드
Cell attachment; Cell proliferation; Non-thermal atmospheric pressure plasma jet; SLA treatment
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